Title to Table!.

Table 1.Bacterial Nucleotide and Protein Sequences That Most Closely Match to Sequences of Individual Clones Derived From Culture of Stealth Virus-1

 

Clone

Nucleotides

Matching Bacterial Sequence (GenBank Accession Number)

Presumed Function and/or Metabolic Pathway -

Designation

sequenced

Nucleotide

Protein

Bacterial Species
   

Accession

Identity

p value

Accession

Identity

p value

  

3B23

8,916

AE000700

40/44

5e-05

Transfer RNA arginine - Aquifex aeolicus

P45493

161/380

7e-82

Hippurate hydrolase - Campylobacter jejuni
         

P31474

163/398

6e-83

YieO Drug resistance translocase - Escherichia coli
         

gi1502421

90/240

2e-37

3-keto acyl reductase (lipid synthesis) – Bacillus subtilis
           

80/242

2e-26

  
         

g1486253

260/521

e-147

L-sorbose dehydrongenase – Gluconobacter oxydans

3B35

2,142

      

e1185288

99/249

4e-44

Hypothetical protein (ymdB gene) - Bacillus subtilis

3B313*

8,905

U00039

66/77

1e-07

YhiJ protein coding region- Escherichia coli
     

42/46

7e-06

      

YhiH protein coding region- Escherichia coli
     

72/86

7e-06

        

60/70

7e-06

YhhJ protein coding region- Escherichia coli
     

35/37

3e-05

        
         

P32246

18/48

3e-06

C-C chemokine receptor type 1#
           

15/54

3e-06

  
         

P37409

79/269

2e-22

Vitamin B12 receptor - Salmonella typhimurium
         

g2851479

242/381

0.0

ABC transporter YhiH - Escherichia coli
           

172/259

0.0

  
           

42/56

0.0

  
           

40/65

0.0

  
         

g586667

157/285

8e-95

Hypothetical 38.8 kd protein (f355) YhiI – E.. coli
         

gi1787767

192/380

2e-121

Protein (30% identity to CDAS_BACSH) - E. coli

3B41

2,923

      

e1240553

115/335

8e-43

Succinoglycan biosynthesis - Rhizobium meliloti
           

88/211

2e-34

  
         

P21362

34/86

1e-10

Protein in trpA-tonB intergenic region - E. coli

3B43

3,620

U28505

1200/1374

0.0

Agrobacterium vitis ribosomal RNA operon
     

481/507

0.0

        
     

313/323

e-157

        
     

309/389

e-118

        
     

148/165

3e-46

        
     

72/76

3e-24

        
     

66/71

8e-19

        

3B47

2,024

      

g3183458

169/406

5e-80

ABC transporter YliA – E. coli

         

g2496748

53/186

4e-18

Y4SH cell wall synthesis NGR234 plasmid - Rhizobium sp.

 

 

 

 

3B512

2,345

M34956

103/122

5e-16

      

Nucleotide binding enzyme (P115) - Mycoplasma hyorhinis
   

AC005605

35/38

4e-04

      

Subtelomeric sequence - Homo sapiens#
         

g1352653

169/313

9e-91

Nucleotide binding enzyme(P115) - Mycoplasma hyorhinis

3B513**

8,106

AE000079

43/46

3e-08

      

Non-coding region in NGR234 plasmid – Rhizobium sp.

          gi2621947

28/127

5e-05

Inosine dehydrogenase - Methanobacterium thermoautotroph.
         

g1042142

90/183

5e-39

DNA invertase PaeR7IN – Pseudomonas aeruginosa

S53714

114/332

4e-33

Hypothetical denitrification protein - Pseudomonas aeruginosa
         

d1025196

46/190

3e-07

CbbO protein – Hydrogenophilis thermoluteolus
         

gi2522277

71/121

1e-31

CbbQ protein – Hydrogenophilis thermoluteolus

3B520

1,254

      

g2492550

87/239

1e-38

ABC transporter P29 - Mycoplasma pneumoniae

3B528

2,049

      

gi1732200

76/251

2e-20

Permease for mannose subunit IIP - Vibrio furnissii
         

gi1732199

51/145

7e-19

Permease for mannose subunit III Man - Vibrio furnissii

3B534

808

      

P33675

144/164

9e-69

Enolase - Zymomonas mobilis

3B614

5,063

L24486

62/69

7e-17

      

Gene fragment containing repeats - Brucella ovis,
         

d1014157

188/311

e-108

Magnetic particle protein AcCoA - Magnetospirillum sp.
         

P21891

137/306

2e-60

Intergrase/recombinase XerD – E. coli
         

g606324

71/179

1e-27

Shikimic acid kinase I - E. coli
         

P07639

160/356

8e-71

3-dehydroquinate synthase - E. coli

3B622.T3

817

      

P75185

57/191

4e-20

Phosphate permease – Mycoplasma pneumoniae

3B622.T7

834

        

49/127

6e-20

  

3B627

332

      

AC002339

23/41

9e-10

ABC Transporter - Arabidopsis thaliana##

3B629

165

      

M13957

35/42

2e-13

RNA polymerase - B. subtilis

3B632

877

      

gi2984206

77/171

1e-38

Rnase HII - Aquifex aeolicus

C1616

4,626

U78089

834/1,039

e-119

      

UDP-glucose epimerase/orf1/orf2 - Brucella abortus
     

400/496

4e-55

        
     

222/280

6e-17

        
     

363/468

6e-17

        
     

139/170

1e-15

        
     

74/86

6e-11

        
   

AE000065

444/525

e-108

      

Transposase of NGR234 plasmid - Rhizobium sp
         

g2708269

48/60

2e-22

Unknown protein – Brucella abortus
         

g2708270

307/335

0.0

UDP-glucose epimerase - Brucella abortus

g2708271

264/315

2e-151

UDP-glucose epimerase - Brucella abortus orf1
         

g2708272

165/185

2e-127

UDP-glucose epimerase - Brucella abortus orf2
           

68/89

e-127

  
         

P55373

130/235

7e-66

Transposase Y4BF of pNGR234 plasmid - Rhizobium sp

C16116.T3

846

L24478

48/51

2e-12

      

Gene fragment repeat region - Brucella abortus
         

d1019327

29/60

8e-09

Exoxyribonuclease III - Synechocystis sp

C16116.T7

774

L24486

53/59

3e-08

      

Gene fragment repeat region - Brucella ovis
         

d1019327

24/59

3e-07

Exoxyribonuclease III - Synechocystis sp

C16118

1,644

      

D90913

152/427

2e-64

Possible membrane transport - Synechocystis sp.

C16122

4,915

      

U93874

152/382

4e-69

Cystathionine gamma-lyase - Bacillus subtilis
         

Q10872

91/284

4e-25

Transcription regulation – Mycobacterium tuberculosis
         

P05640

76/289

8e-22

Dihydrodipicolinate synthase - E. coli
         

P37403

52/140

1e-10

Leucine responsive protein - S. typhimurium
         

AF086832

62/201

3e-21

Putative transporter orf5 - Streptomyces coelicolor

C16125

2,735

L10720

35/38

4e-04

      

Toxin secretion - Bordetella petussis
         

B47301

226/600

e-100

  
         

Z99110

65/111

3e-29

Transglycosylase – Bacillus subtilis

C16127

257

      

g1651858

40/81

7e-14

Sulfate Tranporter - Synechocystis sp.

C16134

4,142

      

Q07607

176/290

2e-99

MosA protein - Rhizobium meliloti
         

AF025847

95/172

1e-47

(p)ppGpp synthetase - Myxococcus xanthus
         

D63898

81/196

2e-30

Membrane lipid synthesis - Deinococcus radiodurans
         

X70031

39/71

6e-28

Small protein B - Mycobacterium tuberculosis
         

P43740

42/90

2e-10

DNA-directed RNA polymerase - H. influenzae

C16135

2,413

      

g1750115

35/85

6e-13

YnaD protein - Bacillus subtilis

C16141

213

U43540

31/33

3e-05

      

dTDP Dehydratase - Streptococcus pneunomia
         

AF030359

49/63

2e-24

  

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Footnote to Table 1.

 

*The T7 end of clone 3B313 matched to the T3 sequence of clone C16246 showing a stretch of 536/540 nucleotide identity (p value e-118). The T3 sequence in clone C16246 showed repeated regions with significant homology to the G-protein coupled receptor homolog (US28 protein) of HCMV (p value 1e-19). This protein shares homology with the human C-C chemokine receptor. Relatively minor sequence differences in the T7 sequence of clone 3B313 explains the preferred matching of its sequence to the human C-C chemokine receptor, rather than to the US28 protein of HCMV. The T3 end of clone C16246 showed highly significant matching to the HCMV genome (157/195 nucleotide identity for internal long repeats p 2e –14). A similar situation exists between clone 3B313 and clones 3B529 and 3B532.

**The T3 end of clone 3B513 matched at 438/467 nucleotides (p 0.0) to a region within the T3 sequence of clone 3B525. The deduced amino acid sequence of the T7 end of clone 3B525, matched to the large tegument protein of HCMV (82/186 amino acid identity, p 4e-44), as did several additional clones.

#eukaryotic human sequence

##eukaryotic plant sequence

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